KPV (5mg)
Technické specifikace
| Čistota (HPLC) | ≥98% (HPLC) |
| CAS číslo | 67727-97-3 |
| Forma | White lyophilized powder |
| Skladování | -20°C |
| Sekvence | Lys-Pro-Val |
| Molekulová hmotnost | 342.43 g/mol |
| Solná forma | Acetate |
| Rozpustnost | Soluble in water |
KPV (5mg)
Katalogová cena v EUR · HU, SK, CZ, PL
- Eurozone (EUR)43,50 EUR
- Maďarsko (HU)43,50 EUR≈ 17 400 Ft
- Slovensko (SK)43,50 EUR
- Česko (CZ)43,50 EUR≈ 1 088 Kč
- Polsko (PL)43,50 EUR≈ 184,88 zł
Stejná katalogová cena v EUR při doručení do Maďarska, Slovenska, Česka a Polska. Platba v EUR.
Orientační HUF/CZK/PLN přepočteno z EUR; Slovensko používá EUR. Kurzy přibližné. Platba v EUR.
α-MSH C-terminal tripeptide (Lys-Pro-Val) for inflammation and gut-health research. 5mg vial.
Pouze pro laboratorní výzkum.
Není určeno pro lidskou spotřebu, veterinární ani diagnostické použití.
From the Peptide Explorer
A tripeptide derived from the C-terminal end of alpha-MSH. Unlike the parent molecule, KPV lacks melanocortin receptor binding but retains potent anti-inflammatory signaling, making it a focus of GI and dermatological research.
Key Mechanisms
- ›NF-κB inhibition (independent of MC receptors)
- ›Intracellular PEP-T1 transporter uptake
- ›Inflammatory cytokine suppression (TNF-α, IL-6, IL-1β)
- ›Direct antimicrobial activity
Primary Research Areas
- ›Inflammatory bowel conditions
- ›Dermatitis
- ›Antimicrobial defense
- ›Mucosal healing
Key Research Findings
- Reduced colonic inflammation in DSS-colitis mouse model (Dalmasso et al., 2008)
- Exhibited direct antimicrobial activity against S. aureus and C. albicans
- Transported into intestinal epithelial cells via PEP-T1 transporter
Research Overview
A tripeptide derived from the C-terminal end of alpha-MSH. Unlike the parent molecule, KPV lacks melanocortin receptor binding but retains potent anti-inflammatory signaling, making it a focus of GI and dermatological research.
Origin: C-terminal fragment of alpha-melanocyte-stimulating hormone (α-MSH)
Mechanism of Action
- NF-κB inhibition (independent of MC receptors)
- Intracellular PEP-T1 transporter uptake
- Inflammatory cytokine suppression (TNF-α, IL-6, IL-1β)
- Direct antimicrobial activity
Primary Research Areas
- Inflammatory bowel conditions
- Dermatitis
- Antimicrobial defense
- Mucosal healing
Key Published Findings
- Reduced colonic inflammation in DSS-colitis mouse model (Dalmasso et al., 2008)
- Exhibited direct antimicrobial activity against S. aureus and C. albicans
- Transported into intestinal epithelial cells via PEP-T1 transporter
Research Protocol
Commonly studied routes: Oral, Topical, Subcutaneous. Reconstitute with bacteriostatic water. Consult published literature for dose ranges; use our Peptide Calculator for volumetric preparation.
Storage
-20°C lyophilized, 2-8°C reconstituted
Important Notice
KPV (5mg) is supplied for laboratory research use only (RUO). Not for human or veterinary use, diagnostics, or therapeutics.
Výzkumné specifikace
Synthesized for strict analytical consistency. Verified via HPLC/MS.Zobrazit standardy kvality →
Manipulace a skladování
- Store lyophilized at -20°C
- Protect from light and moisture
- Use sterile bacteriostatic water for reconstitution
- Minimize freeze-thaw cycles
- Solubility: Soluble in water