Glutathione (1500mg)
Especificaciones técnicas
| Pureza (HPLC) | ≥98% (HPLC) |
| Número CAS | 70-18-8 |
| Forma | White lyophilized powder |
| Almacenamiento | -20°C |
| Secuencia | γGlu-Cys-Gly |
| Peso molecular | 307.32 g/mol |
| Forma salina | Acetate |
| Solubilidad | Highly water-soluble |
Glutathione (1500mg)
Precio de lista en EUR · HU, SK, CZ, PL
- Eurozone (EUR)148,50 EUR
- Hungría (HU)148,50 EUR≈ 59 400 Ft
- Eslovaquia (SK)148,50 EUR
- Chequia (CZ)148,50 EUR≈ 3 713 Kč
- Polonia (PL)148,50 EUR≈ 631,13 zł
Mismo precio de lista en EUR para envío a Hungría, Eslovaquia, República Checa y Polonia. El pago se cobra en EUR.
HUF/CZK/PLN indicativos convertidos desde EUR; Eslovaquia usa EUR. Tasas aproximadas. Cobro en EUR.
Reduced L-glutathione — master antioxidant tripeptide for oxidative-stress and detoxification research. 1500mg vial.
Estrictamente para investigación de laboratorio.
No apto para consumo humano, uso veterinario ni diagnóstico.
From the Peptide Explorer
The most abundant intracellular thiol-based antioxidant, present at 1-10 mM in most mammalian cells. Its free sulfhydryl group on the central cysteine is directly oxidized to GSSG by reactive oxygen species and is regenerated by NADPH-dependent glutathione reductase. Central to Phase-II detoxification, redox signaling, and maintenance of protein thiol status.
Key Mechanisms
- ›Direct quenching of reactive oxygen and nitrogen species
- ›Cofactor for glutathione peroxidase and glutathione S-transferase
- ›Phase-II hepatic conjugation of xenobiotics
- ›Regeneration of vitamin C and vitamin E radicals
- ›Regulation of protein S-glutathionylation
Primary Research Areas
- ›Oxidative stress and ageing
- ›Hepatic detoxification research
- ›Neurodegenerative models (Parkinson's)
- ›Mitochondrial dysfunction
- ›Redox signaling
Key Research Findings
- Intracellular GSH depletion is a hallmark of dopaminergic neurodegeneration in Parkinson's (Sian et al., Ann Neurol 1994)
- Restores mitochondrial respiratory capacity in oxidative-stress models
- Central role in the γ-glutamyl cycle and Phase-II detoxification pathways
Research Overview
The most abundant intracellular thiol-based antioxidant, present at 1-10 mM in most mammalian cells. Its free sulfhydryl group on the central cysteine is directly oxidized to GSSG by reactive oxygen species and is regenerated by NADPH-dependent glutathione reductase. Central to Phase-II detoxification, redox signaling, and maintenance of protein thiol status.
Origin: Endogenous tripeptide antioxidant present in all aerobic cells; the principal intracellular redox buffer
Mechanism of Action
- Direct quenching of reactive oxygen and nitrogen species
- Cofactor for glutathione peroxidase and glutathione S-transferase
- Phase-II hepatic conjugation of xenobiotics
- Regeneration of vitamin C and vitamin E radicals
- Regulation of protein S-glutathionylation
Primary Research Areas
- Oxidative stress and ageing
- Hepatic detoxification research
- Neurodegenerative models (Parkinson's)
- Mitochondrial dysfunction
- Redox signaling
Key Published Findings
- Intracellular GSH depletion is a hallmark of dopaminergic neurodegeneration in Parkinson's (Sian et al., Ann Neurol 1994)
- Restores mitochondrial respiratory capacity in oxidative-stress models
- Central role in the γ-glutamyl cycle and Phase-II detoxification pathways
Research Protocol
Commonly studied routes: Intravenous, Subcutaneous, Oral. Reconstitute with bacteriostatic water. Consult published literature for dose ranges; use our Peptide Calculator for volumetric preparation.
Storage
-20°C lyophilized, protect from air and light
Important Notice
Glutathione (1500mg) is supplied for laboratory research use only (RUO). Not for human or veterinary use, diagnostics, or therapeutics.
Especificaciones de investigación
Synthesized for strict analytical consistency. Verified via HPLC/MS.Ver estándares de calidad →
Manipulación y almacenamiento
- Store lyophilized at -20°C
- Protect from light and moisture
- Use sterile bacteriostatic water for reconstitution
- Minimize freeze-thaw cycles
- Solubility: Highly water-soluble