KPV (10mg)
Specifiche tecniche
| Purezza (HPLC) | ≥98% (HPLC) |
| Numero CAS | 67727-97-3 |
| Forma | White lyophilized powder |
| Conservazione | -20°C |
| Sequenza | Lys-Pro-Val |
| Peso molecolare | 342.43 g/mol |
| Forma salina | Acetate |
| Solubilità | Soluble in water |
KPV (10mg)
Prezzo di listino EUR · HU, SK, CZ, PL
- Eurozone (EUR)87,00 EUR
- Ungheria (HU)87,00 EUR≈ 34 800 Ft
- Slovacchia (SK)87,00 EUR
- Cechia (CZ)87,00 EUR≈ 2 175 Kč
- Polonia (PL)87,00 EUR≈ 369,75 zł
Stesso prezzo di listino in EUR per consegna in Ungheria, Slovacchia, Repubblica Ceca e Polonia. Pagamento in EUR.
HUF/CZK/PLN indicativi convertiti da EUR; la Slovacchia usa EUR. Tassi approssimativi. Pagamento in EUR.
Alpha-MSH C-terminal tripeptide for inflammation research.
Mechanism: Inhibits NF-κB, reduces TNF-α/IL-1β/IL-6, penetrates cell membranes.
Applications: IBD models, wound healing, gut-immune research.
Note: No pigmentation effects unlike full α-MSH.
Solo per ricerca di laboratorio.
Non destinato al consumo umano, uso veterinario o diagnostico.
From the Peptide Explorer
A tripeptide derived from the C-terminal end of alpha-MSH. Unlike the parent molecule, KPV lacks melanocortin receptor binding but retains potent anti-inflammatory signaling, making it a focus of GI and dermatological research.
Key Mechanisms
- ›NF-κB inhibition (independent of MC receptors)
- ›Intracellular PEP-T1 transporter uptake
- ›Inflammatory cytokine suppression (TNF-α, IL-6, IL-1β)
- ›Direct antimicrobial activity
Primary Research Areas
- ›Inflammatory bowel conditions
- ›Dermatitis
- ›Antimicrobial defense
- ›Mucosal healing
Key Research Findings
- Reduced colonic inflammation in DSS-colitis mouse model (Dalmasso et al., 2008)
- Exhibited direct antimicrobial activity against S. aureus and C. albicans
- Transported into intestinal epithelial cells via PEP-T1 transporter
Research Overview
A tripeptide derived from the C-terminal end of alpha-MSH. Unlike the parent molecule, KPV lacks melanocortin receptor binding but retains potent anti-inflammatory signaling, making it a focus of GI and dermatological research.
Origin: C-terminal fragment of alpha-melanocyte-stimulating hormone (α-MSH)
Mechanism of Action
- NF-κB inhibition (independent of MC receptors)
- Intracellular PEP-T1 transporter uptake
- Inflammatory cytokine suppression (TNF-α, IL-6, IL-1β)
- Direct antimicrobial activity
Primary Research Areas
- Inflammatory bowel conditions
- Dermatitis
- Antimicrobial defense
- Mucosal healing
Key Published Findings
- Reduced colonic inflammation in DSS-colitis mouse model (Dalmasso et al., 2008)
- Exhibited direct antimicrobial activity against S. aureus and C. albicans
- Transported into intestinal epithelial cells via PEP-T1 transporter
Research Protocol
Commonly studied routes: Oral, Topical, Subcutaneous. Reconstitute with bacteriostatic water. Consult published literature for dose ranges; use our Peptide Calculator for volumetric preparation.
Storage
-20°C lyophilized, 2-8°C reconstituted
Important Notice
KPV (10mg) is supplied for laboratory research use only (RUO). Not for human or veterinary use, diagnostics, or therapeutics.
Specifiche di ricerca
Synthesized for strict analytical consistency. Verified via HPLC/MS.Vedi standard qualità →
Manipolazione e conservazione
- Store lyophilized at -20°C
- Protect from light and moisture
- Use sterile bacteriostatic water for reconstitution
- Minimize freeze-thaw cycles
- Solubility: Soluble in water
Domande frequenti
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Verified Research Reviews
Fani
"best product for inflammation "