System Entry • 12/27/2025

AOD-9604: Precision Lipolysis Without Growth Effects

Investigating the C-terminal fragment of hGH and its selective ability to mobilize fat stores.

### The Fragment AOD-9604 is a modified form of amino acids 176-191 of the Growth Hormone polypeptide. Researchers developed it to isolate the fat-burning (lipolytic) effects of GH from its growth-promoting (anabolic/IGF-1) effects. ### Mechanism of Action In laboratory studies, AOD-9604 has been shown to: - Stimulate lipolysis (breakdown of fat) in adipocytes. - Inhibit lipogenesis (formation of new fat). Crucially, it does this without affecting blood sugar levels or inducing cell proliferation, making it a safer, more targeted tool for obesity research compared to full-length hGH. *Target adipose research with AOD-9604 from peptide limited.*

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