System Entry • 12/27/2025
Semax & Selank: The Frontier of Nootropic Peptides
Comparing the mechanisms of ACTH-derived analogues in cognitive enhancement and anxiolytic models.
### Semax: Cognitive Clarity
Derived from Adrenocorticotropic Hormone (ACTH), Semax has been studied for its neuroprotective and neurogenic properties. Research suggests it increases Brain-Derived Neurotrophic Factor (BDNF) levels, potentially enhancing memory consolidation, focus, and protection against oxidative stress in neuronal tissue.
### Selank: Anxiolytic Modulation
Selank is also an ACTH analogue but with a focus on anxiety regulation. It appears to modulate the expression of Interleukin-6 and balance neurotransmitters like serotonin and dopamine. Research models show it may reduce anxiety without the sedation typical of benzodiazepines.
### Research Focus
Both peptides are heavily researched for their potential in treating ischemic stroke damage, ADHD, and anxiety disorders.
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