KPV (5mg)
Technische Spezifikationen
| Reinheit (HPLC) | ≥98% (HPLC) |
| CAS-Nummer | 67727-97-3 |
| Form | White lyophilized powder |
| Lagerung | -20°C |
| Sequenz | Lys-Pro-Val |
| Molekulargewicht | 342.43 g/mol |
| Salzform | Acetate |
| Löslichkeit | Soluble in water |
KPV (5mg)
EUR-Listenpreis · HU, SK, CZ, PL
- Eurozone (EUR)48,33 EUR
- Ungarn (HU)48,33 EUR≈ 19 332 Ft
- Slowakei (SK)48,33 EUR
- Tschechien (CZ)48,33 EUR≈ 1 208 Kč
- Polen (PL)48,33 EUR≈ 205,40 zł
Gleicher EUR-Listenpreis für Lieferung nach Ungarn, Slowakei, Tschechien und Polen. Abrechnung in EUR.
HUF/CZK/PLN sind indikativ aus EUR umgerechnet; die Slowakei nutzt EUR. Kurse annähernd. Abrechnung in EUR.
KPV — α-MSH-abgeleitetes Tripeptid mit entzündungshemmenden Eigenschaften; in Modellen zu entzündlichen Darm- und Hauterkrankungen. Nur RUO — ausschließlich für Laborforschung; nicht zum menschlichen Verzehr.
Ausschließlich für Laborforschung.
Nicht für den menschlichen Verzehr, tierärztliche oder diagnostische Zwecke.
From the Peptide Explorer
A tripeptide derived from the C-terminal end of alpha-MSH. Unlike the parent molecule, KPV lacks melanocortin receptor binding but retains potent anti-inflammatory signaling, making it a focus of GI and dermatological research.
Key Mechanisms
- ›NF-κB inhibition (independent of MC receptors)
- ›Intracellular PEP-T1 transporter uptake
- ›Inflammatory cytokine suppression (TNF-α, IL-6, IL-1β)
- ›Direct antimicrobial activity
Primary Research Areas
- ›Inflammatory bowel conditions
- ›Dermatitis
- ›Antimicrobial defense
- ›Mucosal healing
Key Research Findings
- Reduced colonic inflammation in DSS-colitis mouse model (Dalmasso et al., 2008)
- Exhibited direct antimicrobial activity against S. aureus and C. albicans
- Transported into intestinal epithelial cells via PEP-T1 transporter
Research Overview
A tripeptide derived from the C-terminal end of alpha-MSH. Unlike the parent molecule, KPV lacks melanocortin receptor binding but retains potent anti-inflammatory signaling, making it a focus of GI and dermatological research.
Origin: C-terminal fragment of alpha-melanocyte-stimulating hormone (α-MSH)
Mechanism of Action
- NF-κB inhibition (independent of MC receptors)
- Intracellular PEP-T1 transporter uptake
- Inflammatory cytokine suppression (TNF-α, IL-6, IL-1β)
- Direct antimicrobial activity
Primary Research Areas
- Inflammatory bowel conditions
- Dermatitis
- Antimicrobial defense
- Mucosal healing
Key Published Findings
- Reduced colonic inflammation in DSS-colitis mouse model (Dalmasso et al., 2008)
- Exhibited direct antimicrobial activity against S. aureus and C. albicans
- Transported into intestinal epithelial cells via PEP-T1 transporter
Research Protocol
Commonly studied routes: Oral, Topical, Subcutaneous. Reconstitute with bacteriostatic water. Consult published literature for dose ranges; use our Peptide Calculator for volumetric preparation.
Storage
-20°C lyophilized, 2-8°C reconstituted
Important Notice
KPV (5mg) is supplied for laboratory research use only (RUO). Not for human or veterinary use, diagnostics, or therapeutics.
Forschungsspezifikationen
Synthesized for strict analytical consistency. Verified via HPLC/MS.Qualitätsstandards ansehen →
Handhabung & Lagerung
- Store lyophilized at -20°C
- Protect from light and moisture
- Use sterile bacteriostatic water for reconstitution
- Minimize freeze-thaw cycles
- Solubility: Soluble in water