Pinealon (10mg)
Specyfikacja techniczna
| Czystość (HPLC) | ≥98% (HPLC) |
| Numer CAS | 864815-30-1 |
| Forma | White lyophilized powder |
| Przechowywanie | -20°C |
| Sekwencja | Glu-Asp-Arg |
| Masa cząsteczkowa | 418.4 g/mol |
| Forma soli | Acetate |
| Rozpuszczalność | Soluble in water |
Pinealon (10mg)
Cena katalogowa w EUR · HU, SK, CZ, PL
- Eurozone (EUR)49,99 EUR
- Węgry (HU)49,99 EUR≈ 19 996 Ft
- Słowacja (SK)49,99 EUR
- Czechy (CZ)49,99 EUR≈ 1 250 Kč
- Polska (PL)49,99 EUR≈ 212,46 zł
Ta sama cena katalogowa w EUR przy dostawie na Węgry, Słowację, Czechy i Polskę. Płatność w EUR.
Orientacyjne kwoty HUF, CZK i PLN przeliczone z EUR; Słowacja stosuje EUR. Kursy przybliżone. Płatność w EUR.
Pinealon — tripeptyd geroprotekcyjny z klasy Khavinson; badany w modelach funkcji poznawczych i starzenia się. Wyłącznie RUO — do badań laboratoryjnych; nie do spożycia przez ludzi.
Wyłącznie do badań laboratoryjnych.
Nie do spożycia przez ludzi, zastosowań weterynaryjnych ani diagnostycznych.
From the Peptide Explorer
A short bioregulatory tripeptide (EDR) developed within the Khavinson gerontology program. Acts as a gene-targeting regulatory peptide that penetrates cells and nuclei to modulate transcription of neurotrophic and cell-cycle genes, with documented antioxidant and neuroprotective activity in stress and aging models.
Key Mechanisms
- ›Gene-specific transcriptional modulation
- ›Attenuation of oxidative stress markers
- ›Neuroprotection against hypoxic injury
- ›Normalization of melatonin and circadian gene expression
- ›Reduction of neuronal apoptosis
Primary Research Areas
- ›Cognitive aging and dementia models
- ›Oxidative stress research
- ›Circadian rhythm restoration
- ›Neurodegeneration
- ›Geroscience
Key Research Findings
- Reduced oxidative DNA damage in aged rat cortex (Khavinson et al., 2011)
- Improved cognitive performance in chronic hyperhomocysteinemia models (Arutjunyan et al., 2012)
- Normalized clock-gene expression following experimental desynchronization
Research Overview
A short bioregulatory tripeptide (EDR) developed within the Khavinson gerontology program. Acts as a gene-targeting regulatory peptide that penetrates cells and nuclei to modulate transcription of neurotrophic and cell-cycle genes, with documented antioxidant and neuroprotective activity in stress and aging models.
Origin: Short bioregulatory peptide developed by the Khavinson (St Petersburg) laboratory
Mechanism of Action
- Gene-specific transcriptional modulation
- Attenuation of oxidative stress markers
- Neuroprotection against hypoxic injury
- Normalization of melatonin and circadian gene expression
- Reduction of neuronal apoptosis
Primary Research Areas
- Cognitive aging and dementia models
- Oxidative stress research
- Circadian rhythm restoration
- Neurodegeneration
- Geroscience
Key Published Findings
- Reduced oxidative DNA damage in aged rat cortex (Khavinson et al., 2011)
- Improved cognitive performance in chronic hyperhomocysteinemia models (Arutjunyan et al., 2012)
- Normalized clock-gene expression following experimental desynchronization
Research Protocol
Commonly studied routes: Subcutaneous, Intranasal. Reconstitute with bacteriostatic water. Consult published literature for dose ranges; use our Peptide Calculator for volumetric preparation.
Storage
-20°C lyophilized; reconstituted 2-8°C
Important Notice
Pinealon (10mg) is supplied for laboratory research use only (RUO). Not for human or veterinary use, diagnostics, or therapeutics.
Specyfikacja badawcza
Synthesized for strict analytical consistency. Verified via HPLC/MS.Zobacz standardy jakości →
Przechowywanie i obsługa
- Store lyophilized at -20°C
- Protect from light and moisture
- Use sterile bacteriostatic water for reconstitution
- Minimize freeze-thaw cycles
- Solubility: Soluble in water