SS-31 (Elamipretide) (10mg)
Specyfikacja techniczna
| Czystość (HPLC) | ≥98% (HPLC) |
| Numer CAS | 736992-21-5 |
| Forma | White lyophilized powder |
| Przechowywanie | -20°C |
| Sekwencja | D-Arg-Dmt-Lys-Phe-NH₂ |
| Masa cząsteczkowa | 640.81 g/mol |
| Forma soli | Acetate |
| Rozpuszczalność | Soluble in water |
SS-31 (Elamipretide) (10mg)
Cena katalogowa w EUR · HU, SK, CZ, PL
- Eurozone (EUR)117,00 EUR
- Węgry (HU)117,00 EUR≈ 46 800 Ft
- Słowacja (SK)117,00 EUR
- Czechy (CZ)117,00 EUR≈ 2 925 Kč
- Polska (PL)117,00 EUR≈ 497,25 zł
Ta sama cena katalogowa w EUR przy dostawie na Węgry, Słowację, Czechy i Polskę. Płatność w EUR.
Orientacyjne kwoty HUF, CZK i PLN przeliczone z EUR; Słowacja stosuje EUR. Kursy przybliżone. Płatność w EUR.
SS-31 (Elamipretide) — tetrapeptyd wiążący kardiolipinę na wewnętrznej błonie mitochondrialnej; stabilizuje łańcuch oddechowy w modelach stresu oksydacyjnego. Inna klasa mechanistyczna niż MOTS-c. Wyłącznie RUO — do badań laboratoryjnych; nie do spożycia przez ludzi.
Wyłącznie do badań laboratoryjnych.
Nie do spożycia przez ludzi, zastosowań weterynaryjnych ani diagnostycznych.
From the Peptide Explorer
A mitochondria-targeted tetrapeptide that concentrates >1000-fold in the inner mitochondrial membrane, selectively binding cardiolipin. By stabilizing cardiolipin-cytochrome c interactions, SS-31 optimizes electron transport chain efficiency and reduces ROS production at the source.
Key Mechanisms
- ›Cardiolipin binding in inner mitochondrial membrane
- ›Electron transport chain optimization
- ›ROS reduction at source (not scavenging)
- ›Cytochrome c stabilization
- ›Mitochondrial membrane potential preservation
Primary Research Areas
- ›Mitochondrial dysfunction
- ›Heart failure
- ›Renal ischemia
- ›Barth syndrome
- ›Age-related mitochondrial decline
Key Research Findings
- Concentrated >1000-fold in mitochondria within minutes
- Improved cardiac function in heart failure models (Dai et al., JACC, 2013)
- Advanced to Phase 3 clinical trials for Barth syndrome
Research Overview
A mitochondria-targeted tetrapeptide that concentrates >1000-fold in the inner mitochondrial membrane, selectively binding cardiolipin. By stabilizing cardiolipin-cytochrome c interactions, SS-31 optimizes electron transport chain efficiency and reduces ROS production at the source.
Origin: Developed by Dr. Hazel Szeto at Weill Cornell Medicine
Mechanism of Action
- Cardiolipin binding in inner mitochondrial membrane
- Electron transport chain optimization
- ROS reduction at source (not scavenging)
- Cytochrome c stabilization
- Mitochondrial membrane potential preservation
Primary Research Areas
- Mitochondrial dysfunction
- Heart failure
- Renal ischemia
- Barth syndrome
- Age-related mitochondrial decline
Key Published Findings
- Concentrated >1000-fold in mitochondria within minutes
- Improved cardiac function in heart failure models (Dai et al., JACC, 2013)
- Advanced to Phase 3 clinical trials for Barth syndrome
Research Protocol
Commonly studied routes: Subcutaneous, Intravenous. Reconstitute with bacteriostatic water. Consult published literature for dose ranges; use our Peptide Calculator for volumetric preparation.
Storage
-20°C lyophilized
Important Notice
SS-31 (Elamipretide) (10mg) is supplied for laboratory research use only (RUO). Not for human or veterinary use, diagnostics, or therapeutics.
Specyfikacja badawcza
Synthesized for strict analytical consistency. Verified via HPLC/MS.Zobacz standardy jakości →
Przechowywanie i obsługa
- Store lyophilized at -20°C
- Protect from light and moisture
- Use sterile bacteriostatic water for reconstitution
- Minimize freeze-thaw cycles
- Solubility: Soluble in water