Selank (5mg)

Research Overview

A heptapeptide developed at the Institute of Molecular Genetics (Russian Academy of Sciences) based on the endogenous immunomodulatory peptide tuftsin. The addition of the Pro-Gly-Pro sequence enhances metabolic stability while retaining and extending the biological profile of the parent molecule.

Origin: Synthetic analog of tuftsin with added Pro-Gly-Pro

Mechanism of Action

• GABA-A receptor allosteric modulation

• BDNF upregulation

• Enkephalin system modulation

• IL-6 regulation

• Serotonin metabolism modulation

Primary Research Areas

• Anxiolysis

• Cognitive enhancement

• Immune modulation

• Neurotrophic factor regulation

• Memory consolidation

Key Published Findings

• Demonstrated anxiolytic effects comparable to benzodiazepines without sedation in rodent models

• Upregulated BDNF expression in hippocampal neurons

• Modulated IL-6 expression in immune cell cultures

Research Protocol

Commonly studied routes: Intranasal, Subcutaneous. Reconstitute with bacteriostatic water. Consult published literature for dose ranges; use our Peptide Calculator for volumetric preparation.

Storage

-20°C lyophilized

Important Notice

Selank (5mg) is supplied for laboratory research use only (RUO). Not for human or veterinary use, diagnostics, or therapeutics.